Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.583


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELK1chrX_-_473949370.505.0e-02Click!
ELK4chr1_-_2038686220.312.4e-01Click!
GABPB1chr15_-_484348960.234.0e-01Click!
GABPAchr21_+_260291280.165.7e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_1300680 4.837 NM_017900
AURKAIP1
aurora kinase A interacting protein 1
chr22_+_20350272 3.892 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr2_+_113648036 3.391 PSD4
pleckstrin and Sec7 domain containing 4
chr9_-_133141726 3.363 NM_033387
FAM78A
family with sequence similarity 78, member A
chr19_+_63386193 3.224 NM_016324
NM_016325
NM_133502
ZNF274


zinc finger protein 274


chr22_-_20235372 3.192 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr1_-_28842103 3.008 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr6_-_31728447 2.923 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chr6_-_31728418 2.904 BAG6
BCL2-associated athanogene 6
chr3_+_47004457 2.885 NBEAL2
neurobeachin-like 2
chr6_-_31728405 2.882 BAG6
BCL2-associated athanogene 6
chr6_-_31728363 2.847 BAG6
BCL2-associated athanogene 6
chr2_+_113648020 2.685 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr6_-_33375106 2.653 NM_004761
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr3_+_9379706 2.645 NM_001114092
NM_015453
THUMPD3

THUMP domain containing 3

chr1_-_27159462 2.612 NM_152365
C1orf172
chromosome 1 open reading frame 172
chr6_-_168219380 2.595 NM_001122841
FRMD1
FERM domain containing 1
chr16_+_29373365 2.554 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr6_-_31728121 2.551 NM_001098534
BAG6
BCL2-associated athanogene 6
chr22_+_17799341 2.431 MRPL40
mitochondrial ribosomal protein L40
chr22_-_18484428 2.315 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr2_+_113058470 2.300 NM_032309
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr8_+_144444909 2.283 NM_030895
ZNF696
zinc finger protein 696
chr15_+_63948823 2.264 NM_004663
RAB11A
RAB11A, member RAS oncogene family
chr2_+_113058642 2.240 CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr19_+_19357629 2.202 NM_017660
GATAD2A
GATA zinc finger domain containing 2A
chr22_-_17799215 2.179 NM_003325
HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr17_-_3814334 2.176 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr22_-_17799177 2.156 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr9_+_126671321 2.124 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr6_-_33398656 2.115 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr1_-_118273701 2.022 GDAP2
ganglioside induced differentiation associated protein 2
chr7_-_134505923 1.993 C7orf49
chromosome 7 open reading frame 49
chr10_-_98470164 1.973 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr3_-_28365510 1.966 NM_001134432
NM_001134433
NM_022461
AZI2


5-azacytidine induced 2


chr1_-_220829704 1.962 NM_005681
NM_139352
TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

chr22_-_17798998 1.944 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_118273869 1.937 WDR3
WD repeat domain 3
chr7_-_72063147 1.916 NSUN5P2
NOP2/Sun domain family, member 5 pseudogene 2
chr7_+_50318801 1.913 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr7_-_134506001 1.892 C7orf49
chromosome 7 open reading frame 49
chr7_-_134506012 1.865 C7orf49
chromosome 7 open reading frame 49
chr21_+_44256630 1.862 NM_003274
TRAPPC10
trafficking protein particle complex 10
chr1_+_118273887 1.849 NM_006784
WDR3
WD repeat domain 3
chr21_+_45184394 1.837


chr9_-_67945114 1.825 LOC283788
LOC642236
FSHD region gene 1 pseudogene
FSHD region gene 1 pseudogene
chr12_+_119562737 1.824 NM_001033677
CABP1
calcium binding protein 1
chr16_+_2593351 1.813 LOC652276
hypothetical LOC652276
chr20_+_60311419 1.806 NM_007002
NM_175573
ADRM1

adhesion regulating molecule 1

chr11_+_118394703 1.775 TRAPPC4
trafficking protein particle complex 4
chr7_+_74877568 1.771 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
chr21_+_44256601 1.756 TRAPPC10
trafficking protein particle complex 10
chr11_+_118394637 1.751 TRAPPC4
trafficking protein particle complex 4
chr20_+_60311469 1.743 ADRM1
adhesion regulating molecule 1
chr1_-_3702908 1.742 NM_020710
LRRC47
leucine rich repeat containing 47
chr20_+_60311443 1.731 ADRM1
adhesion regulating molecule 1
chr22_+_25398690 1.706 LOC388889
hypothetical LOC388889
chr4_-_915868 1.686 GAK
cyclin G associated kinase
chr20_+_60311334 1.674 ADRM1
adhesion regulating molecule 1
chr9_+_126671297 1.668 NM_030978
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr6_-_31741545 1.608 GPANK1
G patch domain and ankyrin repeats 1
chr1_-_25431544 1.607 NM_015484
NM_207170
SYF2

SYF2 homolog, RNA splicing factor (S. cerevisiae)

chr16_-_30274064 1.600 CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr9_+_126671209 1.585 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr7_+_104959767 1.579 NM_021930
RINT1
RAD50 interactor 1
chr21_-_45184113 1.577 C21orf67
chromosome 21 open reading frame 67
chr16_-_30301357 1.571 SEPT1
septin 1
chr7_+_107171809 1.556 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr12_+_119609341 1.534 MLEC
malectin
chr22_-_19543069 1.522 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_40431618 1.503 LSR
lipolysis stimulated lipoprotein receptor
chr3_+_47299333 1.494 NM_025010
KLHL18
kelch-like 18 (Drosophila)
chr6_-_28475478 1.480 NM_001163391
ZSCAN12
zinc finger and SCAN domain containing 12
chr17_+_31964909 1.466


chr7_-_45117822 1.461 NM_004749
NM_030900
NM_199122
TBRG4


transforming growth factor beta regulator 4


chr8_+_145674247 1.455 PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr20_-_61809648 1.449 ARFRP1
ADP-ribosylation factor related protein 1
chr3_+_181802592 1.448 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr22_+_21852911 1.439 BCR
breakpoint cluster region
chr19_+_63386256 1.430 ZNF274
zinc finger protein 274
chr5_-_180220881 1.429 NM_001172638
NM_152283
ZFP62

zinc finger protein 62 homolog (mouse)

chr20_-_2729227 1.428 CPXM1
carboxypeptidase X (M14 family), member 1
chr9_+_130124873 1.419 COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr6_-_30693003 1.416 PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr6_+_31741814 1.415 CSNK2B
casein kinase 2, beta polypeptide
chr22_+_18091065 1.410 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr22_+_20068039 1.401 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr19_+_10402334 1.399 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_-_31618203 1.398 NM_004640
NM_080598
DDX39B

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

chr9_+_70509925 1.396 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr12_-_40824699 1.396 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr3_-_47299259 1.394 NM_001134878
NM_022342
NM_182902
KIF9


kinesin family member 9


chr7_+_65784500 1.382 RABGEF1
RAB guanine nucleotide exchange factor (GEF) 1
chr22_+_19543248 1.372 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr2_+_176842368 1.372 NM_006554
MTX2
metaxin 2
chr5_-_1687040 1.366 LOC728613
programmed cell death 6 pseudogene
chr7_-_45117797 1.366 TBRG4
transforming growth factor beta regulator 4
chr22_-_17546276 1.363 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_+_18124225 1.359 NM_005992
NM_080646
NM_080647
TBX1


T-box 1


chr21_+_45184324 1.353 NM_058190
C21orf70
chromosome 21 open reading frame 70
chr2_-_27147995 1.353 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_-_118394242 1.346 NM_001028
RPS25
ribosomal protein S25
chr20_-_2729266 1.342 NM_001184699
NM_019609
CPXM1

carboxypeptidase X (M14 family), member 1

chr9_-_130124820 1.341 TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr20_+_28225511 1.338 LOC283788
FRG1B
FSHD region gene 1 pseudogene
FSHD region gene 1 family, member B
chr10_+_1024334 1.332 NM_012341
GTPBP4
GTP binding protein 4
chr20_+_60395515 1.325 NM_001024
RPS21
ribosomal protein S21
chr22_+_19543350 1.314 SNAP29
synaptosomal-associated protein, 29kDa
chr2_-_68332985 1.314 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr17_-_53420595 1.308 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr1_+_37712661 1.307 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr3_-_28365284 1.305 AZI2
5-azacytidine induced 2
chr7_+_107997544 1.304 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr11_+_118394350 1.302 NM_016146
TRAPPC4
trafficking protein particle complex 4
chr7_-_91713044 1.300 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr6_-_30692995 1.286 NM_002714
PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr10_+_1024357 1.274 GTPBP4
GTP binding protein 4
chr1_-_184610953 1.273 TPR
translocated promoter region (to activated MET oncogene)
chr3_-_197714762 1.264 NM_152617
RNF168
ring finger protein 168
chr22_-_19543099 1.261 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_166675980 1.255 NM_145169
SFT2D1
SFT2 domain containing 1
chr12_-_70343656 1.254


chr22_+_20326572 1.234 SDF2L1
stromal cell-derived factor 2-like 1
chr5_+_324775 1.222 PDCD6
programmed cell death 6
chr21_+_32687282 1.220 C21orf119
chromosome 21 open reading frame 119
chr20_+_60395623 1.219 RPS21
ribosomal protein S21
chr1_-_234834410 1.216 NM_018072
HEATR1
HEAT repeat containing 1
chr1_-_184610796 1.205 TPR
translocated promoter region (to activated MET oncogene)
chr10_-_79459296 1.204 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr12_-_122415327 1.199 SBNO1
strawberry notch homolog 1 (Drosophila)
chr17_-_76883656 1.199 SLC38A10
solute carrier family 38, member 10
chr7_+_6583560 1.194 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr6_-_139351084 1.191 NM_001128617
NM_031922
REPS1

RALBP1 associated Eps domain containing 1

chr19_-_59355246 1.190 NM_024316
LENG1
leukocyte receptor cluster (LRC) member 1
chr5_+_324764 1.190 PDCD6
programmed cell death 6
chr16_-_87405817 1.188 NM_000485
NM_001030018
APRT

adenine phosphoribosyltransferase

chr6_+_18263514 1.188 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr6_-_31617748 1.187 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr1_+_20385164 1.187 NM_152376
UBXN10
UBX domain protein 10
chr9_+_130124566 1.183 NM_016035
COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr16_+_30112707 1.177 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr10_-_1024280 1.177 LOC100288619
hypothetical LOC100288619
chr6_+_151815298 1.175 C6orf211
chromosome 6 open reading frame 211
chr12_+_119609305 1.173 NM_014730
MLEC
malectin
chr1_+_45542138 1.171 LOC400752
hypothetical LOC400752
chr22_+_20326591 1.169 SDF2L1
stromal cell-derived factor 2-like 1
chr19_-_1827133 1.157


chr3_+_38055699 1.154 NM_007335
NM_007337
DLEC1

deleted in lung and esophageal cancer 1

chr22_+_19191884 1.153 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr6_-_31617704 1.150 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr16_+_2672476 1.150 NM_018992
KCTD5
potassium channel tetramerisation domain containing 5
chr22_+_20326541 1.148 NM_022044
SDF2L1
stromal cell-derived factor 2-like 1
chr1_+_37712767 1.144 ZC3H12A
zinc finger CCCH-type containing 12A
chr20_+_62082847 1.143 NM_012469
PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr22_+_20326615 1.141 SDF2L1
stromal cell-derived factor 2-like 1
chr22_+_19191859 1.140 MED15
mediator complex subunit 15
chr19_-_40928131 1.137 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr2_+_98591516 1.137 UNC50
unc-50 homolog (C. elegans)
chr2_+_74535700 1.137 NM_031288
INO80B
INO80 complex subunit B
chr7_+_107997527 1.137 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr22_-_17546234 1.135 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_-_97439590 1.134


chr17_+_31965453 1.126 NM_178517
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr7_-_99355085 1.126 NM_033017
NM_033091
TRIM4

tripartite motif containing 4

chr7_-_97439573 1.124 MGC72080
MGC72080 pseudogene
chr1_-_39910296 1.123 NM_032526
NT5C1A
5'-nucleotidase, cytosolic IA
chr17_+_38575939 1.123 NM_031862
NM_031858
NBR1

neighbor of BRCA1 gene 1

chr22_+_19191875 1.122 MED15
mediator complex subunit 15
chr1_+_37712716 1.120 ZC3H12A
zinc finger CCCH-type containing 12A
chr10_-_1024261 1.119


chr15_+_55786212 1.119 GRINL1A
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
chr2_+_187162969 1.118 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr6_+_33352886 1.110 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr1_+_26019209 1.105 NM_019557
FAM54B
family with sequence similarity 54, member B
chr22_-_20551937 1.103 MAPK1
mitogen-activated protein kinase 1
chr20_-_34005799 1.101 NM_016558
NM_033630
SCAND1

SCAN domain containing 1

chr6_-_150011551 1.100 KATNA1
katanin p60 (ATPase containing) subunit A 1
chr1_+_36169260 1.099 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr2_+_98591492 1.090 UNC50
unc-50 homolog (C. elegans)
chr22_+_19191886 1.088 MED15
mediator complex subunit 15
chr15_+_21361901 1.083 MKRN3
makorin ring finger protein 3
chr1_+_222368413 1.082 NM_001136115
NM_015176
FBXO28

F-box protein 28

chr2_+_98591473 1.082 NM_014044
UNC50
unc-50 homolog (C. elegans)
chr11_-_9292694 1.081 TMEM41B
transmembrane protein 41B
chr17_-_30929669 1.081 NM_000286
PEX12
peroxisomal biogenesis factor 12
chr1_-_53458822 1.078 NM_017887
C1orf123
chromosome 1 open reading frame 123
chr11_+_817584 1.077 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr20_+_62082908 1.076 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr22_-_20551722 1.072 MAPK1
mitogen-activated protein kinase 1
chr6_+_31741635 1.066 NM_001320
CSNK2B
casein kinase 2, beta polypeptide
chr5_-_496168 1.059 NM_138464
C5orf55
chromosome 5 open reading frame 55
chr6_-_43763442 1.058 MRPS18A
mitochondrial ribosomal protein S18A
chr22_-_20551953 1.051 NM_002745
NM_138957
MAPK1

mitogen-activated protein kinase 1

chr7_+_107171514 1.051 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr20_+_43028533 1.050 NM_006282
STK4
serine/threonine kinase 4
chr22_+_19191898 1.049 MED15
mediator complex subunit 15
chr19_-_53516962 1.048 CCDC114
coiled-coil domain containing 114
chr20_+_30019465 1.045 NM_001011718
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr9_-_122595475 1.042 NM_012164
FBXW2
F-box and WD repeat domain containing 2
chr5_+_137829065 1.040 EGR1
early growth response 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 1.57e-30 GO:0044260 cellular macromolecule metabolic process
1.39 3.00e-23 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 8.67e-23 GO:0043170 macromolecule metabolic process
1.43 1.72e-21 GO:0090304 nucleic acid metabolic process
1.21 3.05e-20 GO:0044237 cellular metabolic process
1.34 2.93e-15 GO:0044267 cellular protein metabolic process
1.90 1.40e-14 GO:0016032 viral reproduction
1.29 1.62e-14 GO:0034641 cellular nitrogen compound metabolic process
1.41 2.66e-14 GO:0016070 RNA metabolic process
1.16 6.57e-14 GO:0008152 metabolic process
1.28 8.30e-14 GO:0006807 nitrogen compound metabolic process
1.38 2.78e-13 GO:0010467 gene expression
1.74 7.25e-13 GO:0016071 mRNA metabolic process
1.17 7.61e-13 GO:0044238 primary metabolic process
2.21 1.59e-12 GO:0000375 RNA splicing, via transesterification reactions
2.22 2.28e-12 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.22 2.28e-12 GO:0000398 nuclear mRNA splicing, via spliceosome
1.97 3.87e-12 GO:0008380 RNA splicing
1.63 3.37e-11 GO:0006396 RNA processing
1.80 1.74e-10 GO:0006397 mRNA processing
1.09 2.06e-10 GO:0009987 cellular process
1.61 1.36e-09 GO:0009057 macromolecule catabolic process
1.35 1.64e-09 GO:0009059 macromolecule biosynthetic process
1.23 1.77e-09 GO:0071840 cellular component organization or biogenesis
1.42 3.32e-09 GO:0044248 cellular catabolic process
1.64 3.46e-09 GO:0044265 cellular macromolecule catabolic process
1.34 4.90e-09 GO:0034645 cellular macromolecule biosynthetic process
1.49 4.95e-09 GO:0015031 protein transport
1.48 7.63e-09 GO:0045184 establishment of protein localization
1.25 9.68e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.63 1.34e-08 GO:0006974 response to DNA damage stimulus
1.42 6.46e-08 GO:0007049 cell cycle
1.35 7.82e-08 GO:0009056 catabolic process
1.21 9.56e-08 GO:0016043 cellular component organization
1.23 1.02e-07 GO:0019538 protein metabolic process
1.56 1.69e-07 GO:0000278 mitotic cell cycle
1.40 2.44e-07 GO:0008104 protein localization
1.47 4.64e-07 GO:0046907 intracellular transport
1.71 5.17e-07 GO:0010564 regulation of cell cycle process
1.24 8.49e-07 GO:0071842 cellular component organization at cellular level
1.35 9.58e-07 GO:0033036 macromolecule localization
1.30 2.05e-06 GO:0006996 organelle organization
1.44 2.06e-06 GO:0033554 cellular response to stress
1.86 4.63e-06 GO:0000075 cell cycle checkpoint
1.75 5.06e-06 GO:0032446 protein modification by small protein conjugation
1.83 6.87e-06 GO:0071156 regulation of cell cycle arrest
1.49 7.89e-06 GO:0051726 regulation of cell cycle
1.77 8.85e-06 GO:0016567 protein ubiquitination
1.46 8.88e-06 GO:0022403 cell cycle phase
1.66 1.32e-05 GO:0006281 DNA repair
1.26 1.57e-05 GO:0043412 macromolecule modification
1.86 2.42e-05 GO:0022613 ribonucleoprotein complex biogenesis
1.62 2.93e-05 GO:0030163 protein catabolic process
1.65 3.39e-05 GO:0070647 protein modification by small protein conjugation or removal
1.26 4.95e-05 GO:0006464 protein modification process
1.64 5.09e-05 GO:0044257 cellular protein catabolic process
1.64 6.30e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.40 6.38e-05 GO:0022402 cell cycle process
1.47 6.39e-05 GO:0006259 DNA metabolic process
2.12 6.62e-05 GO:0000084 S phase of mitotic cell cycle
1.64 1.19e-04 GO:0006412 translation
2.08 1.39e-04 GO:0051320 S phase
1.79 1.45e-04 GO:0071843 cellular component biogenesis at cellular level
1.62 1.58e-04 GO:0043632 modification-dependent macromolecule catabolic process
1.40 1.90e-04 GO:0016192 vesicle-mediated transport
1.21 2.02e-04 GO:0044249 cellular biosynthetic process
1.62 2.15e-04 GO:0019941 modification-dependent protein catabolic process
1.62 2.66e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.20 2.76e-04 GO:0009058 biosynthetic process
1.17 2.83e-04 GO:0060255 regulation of macromolecule metabolic process
1.63 3.01e-04 GO:0051329 interphase of mitotic cell cycle
1.30 3.48e-04 GO:0051641 cellular localization
1.62 4.02e-04 GO:0051325 interphase
1.57 4.37e-04 GO:0044419 interspecies interaction between organisms
1.32 4.41e-04 GO:0051649 establishment of localization in cell
1.48 4.65e-04 GO:0034621 cellular macromolecular complex subunit organization
1.66 5.19e-04 GO:0007346 regulation of mitotic cell cycle
2.22 9.62e-04 GO:0006354 transcription elongation, DNA-dependent
1.98 1.14e-03 GO:0031570 DNA integrity checkpoint
2.01 1.25e-03 GO:0032984 macromolecular complex disassembly
2.01 1.25e-03 GO:0034623 cellular macromolecular complex disassembly
2.22 1.43e-03 GO:0006353 transcription termination, DNA-dependent
2.07 1.43e-03 GO:0043241 protein complex disassembly
2.07 1.43e-03 GO:0043624 cellular protein complex disassembly
1.49 1.45e-03 GO:0016044 cellular membrane organization
2.13 1.49e-03 GO:0006415 translational termination
2.15 1.49e-03 GO:0019080 viral genome expression
2.15 1.49e-03 GO:0019083 viral transcription
1.15 1.69e-03 GO:0019222 regulation of metabolic process
1.48 1.96e-03 GO:0061024 membrane organization
2.03 1.97e-03 GO:0006414 translational elongation
2.17 2.20e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.98 2.54e-03 GO:0000077 DNA damage checkpoint
1.58 2.83e-03 GO:0048285 organelle fission
1.87 2.84e-03 GO:0019058 viral infectious cycle
1.87 2.84e-03 GO:0048193 Golgi vesicle transport
2.22 3.14e-03 GO:0006302 double-strand break repair
1.34 3.18e-03 GO:0043933 macromolecular complex subunit organization
1.15 3.96e-03 GO:0031323 regulation of cellular metabolic process
1.31 4.62e-03 GO:0032774 RNA biosynthetic process
1.36 5.46e-03 GO:0006915 apoptosis
2.28 6.38e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
2.03 6.41e-03 GO:0051438 regulation of ubiquitin-protein ligase activity
1.81 7.83e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.73 7.93e-03 GO:0043687 post-translational protein modification
1.59 9.74e-03 GO:0009166 nucleotide catabolic process
1.35 1.07e-02 GO:0012501 programmed cell death
1.75 1.16e-02 GO:0022415 viral reproductive process
1.84 1.19e-02 GO:0007093 mitotic cell cycle checkpoint
2.50 1.42e-02 GO:0006369 termination of RNA polymerase II transcription
1.79 1.44e-02 GO:0031016 pancreas development
2.06 1.47e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.84 1.69e-02 GO:0042254 ribosome biogenesis
1.14 1.80e-02 GO:0080090 regulation of primary metabolic process
2.05 2.16e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.05 2.16e-02 GO:0071779 G1/S transition checkpoint
1.59 2.26e-02 GO:0006195 purine nucleotide catabolic process
1.94 2.40e-02 GO:0051340 regulation of ligase activity
1.72 2.61e-02 GO:0010498 proteasomal protein catabolic process
1.72 2.61e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.53 2.64e-02 GO:0000280 nuclear division
1.53 2.64e-02 GO:0007067 mitosis
1.37 2.72e-02 GO:0071822 protein complex subunit organization
1.99 2.82e-02 GO:0071826 ribonucleoprotein complex subunit organization
1.52 2.94e-02 GO:0000087 M phase of mitotic cell cycle
2.01 2.95e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.28 3.12e-02 GO:0006914 autophagy
1.30 3.18e-02 GO:0008219 cell death
2.11 3.39e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.53 3.48e-02 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.53 3.48e-02 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.57 3.52e-02 GO:0072523 purine-containing compound catabolic process
1.63 3.75e-02 GO:0006457 protein folding
1.65 3.82e-02 GO:0022411 cellular component disassembly
1.65 3.82e-02 GO:0071845 cellular component disassembly at cellular level
1.60 3.90e-02 GO:0009261 ribonucleotide catabolic process
2.00 4.31e-02 GO:0022618 ribonucleoprotein complex assembly
2.02 4.49e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.29 4.61e-02 GO:0016265 death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.14e-49 GO:0044424 intracellular part
1.16 2.73e-49 GO:0005622 intracellular
1.22 3.65e-44 GO:0043227 membrane-bounded organelle
1.22 6.38e-44 GO:0043231 intracellular membrane-bounded organelle
1.19 1.38e-42 GO:0043229 intracellular organelle
1.19 1.72e-42 GO:0043226 organelle
1.27 3.28e-31 GO:0005634 nucleus
1.47 2.86e-27 GO:0044428 nuclear part
1.24 1.35e-24 GO:0044446 intracellular organelle part
1.24 3.82e-24 GO:0044422 organelle part
1.43 1.57e-23 GO:0070013 intracellular organelle lumen
1.47 1.54e-22 GO:0031981 nuclear lumen
1.41 3.70e-22 GO:0031974 membrane-enclosed lumen
1.41 6.56e-22 GO:0043233 organelle lumen
1.16 1.39e-20 GO:0005737 cytoplasm
1.86 2.42e-18 GO:0030529 ribonucleoprotein complex
1.49 7.84e-17 GO:0005654 nucleoplasm
1.19 7.86e-17 GO:0044444 cytoplasmic part
1.34 2.10e-13 GO:0005829 cytosol
1.23 1.40e-11 GO:0032991 macromolecular complex
2.37 2.29e-11 GO:0005681 spliceosomal complex
1.24 7.20e-09 GO:0043228 non-membrane-bounded organelle
1.24 7.20e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.04 2.05e-08 GO:0044464 cell part
1.04 2.21e-08 GO:0005623 cell
2.49 2.01e-07 GO:0071013 catalytic step 2 spliceosome
1.56 3.58e-07 GO:0005730 nucleolus
1.79 3.92e-06 GO:0016604 nuclear body
1.95 4.65e-06 GO:0044445 cytosolic part
1.41 2.22e-05 GO:0044451 nucleoplasm part
2.95 2.83e-04 GO:0030532 small nuclear ribonucleoprotein complex
1.20 4.34e-04 GO:0031090 organelle membrane
1.40 4.68e-04 GO:0044431 Golgi apparatus part
1.72 5.84e-04 GO:0005840 ribosome
1.30 1.11e-03 GO:0005794 Golgi apparatus
1.39 1.53e-03 GO:0005694 chromosome
1.34 2.30e-03 GO:0031967 organelle envelope
2.10 2.57e-03 GO:0022626 cytosolic ribosome
1.33 3.51e-03 GO:0031975 envelope
1.95 6.17e-03 GO:0042470 melanosome
1.95 6.17e-03 GO:0048770 pigment granule
1.15 6.66e-03 GO:0043234 protein complex
2.98 6.76e-03 GO:0005689 U12-type spliceosomal complex
1.80 6.84e-03 GO:0016607 nuclear speck
1.74 7.11e-03 GO:0000151 ubiquitin ligase complex
1.22 1.28e-02 GO:0005739 mitochondrion
4.57 1.61e-02 GO:0005885 Arp2/3 protein complex
1.37 2.14e-02 GO:0000139 Golgi membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 2.84e-27 GO:0005515 protein binding
1.08 3.54e-13 GO:0005488 binding
1.25 2.77e-12 GO:0003676 nucleic acid binding
1.48 4.61e-09 GO:0003723 RNA binding
1.79 2.69e-06 GO:0019787 small conjugating protein ligase activity
1.81 2.93e-06 GO:0004842 ubiquitin-protein ligase activity
1.64 1.73e-04 GO:0016881 acid-amino acid ligase activity
1.20 2.98e-04 GO:0000166 nucleotide binding
1.11 1.09e-03 GO:0003824 catalytic activity
1.55 1.41e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.41 7.93e-03 GO:0016874 ligase activity
1.17 8.15e-03 GO:0003677 DNA binding
1.73 8.65e-03 GO:0003735 structural constituent of ribosome
1.67 1.28e-02 GO:0008168 methyltransferase activity
1.18 2.34e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.53 3.39e-02 GO:0019900 kinase binding
1.62 3.59e-02 GO:0016741 transferase activity, transferring one-carbon groups